Richard B Lock Selected Research

Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

2/2016

Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

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Richard B Lock Research Topics

Disease

51	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 02/2024 - 05/2004
45	Leukemia 02/2024 - 06/2002
43	Neoplasms (Cancer) 02/2024 - 08/2006
14	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 02/2024 - 10/2011
10	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 04/2007
6	Hematologic Neoplasms (Hematological Malignancy) 08/2023 - 01/2012
6	Neuroblastoma 01/2016 - 11/2007
5	Glucocorticoid Receptor Deficiency 01/2022 - 03/2005
3	Ewing Sarcoma (Sarcoma, Ewing) 02/2015 - 11/2011
2	Rheumatoid Arthritis 02/2024 - 01/2021
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/2023 - 01/2016
2	Philadelphia Chromosome 11/2021 - 01/2020
2	Carcinogenesis 06/2014 - 04/2013
2	Lymphoma (Lymphomas) 05/2009 - 12/2003
2	Acute Promyelocytic Leukemia 01/2008 - 04/2007
1	Eosinophilia 02/2024
1	Alcoholism (Alcohol Abuse) 02/2024
1	Myeloid Leukemia (Leukemia, Myelocytic) 02/2024
1	Preleukemia 01/2023
1	Acute Erythroblastic Leukemia (Erythroleukemia) 01/2020

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2018 - 12/2003
10	N- propyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (PPTP)IBA 03/2016 - 05/2008
9	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 03/2005
8	GlucocorticoidsIBA 01/2020 - 03/2005
7	Biomarkers (Surrogate Marker)IBA 11/2023 - 09/2014
6	Vincristine (Oncovin)FDA LinkGeneric 09/2015 - 06/2002
5	Phosphotransferases (Kinase)IBA 08/2023 - 12/2003
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2023 - 05/2007
5	Histone Deacetylase InhibitorsIBA 01/2022 - 09/2009
4	ChromatinIBA 02/2024 - 12/2018
4	Cytarabine (Cytosar-U)FDA LinkGeneric 02/2024 - 01/2015
4	RNA (Ribonucleic Acid)IBA 11/2020 - 08/2006
3	Daunorubicin (Cerubidine)FDA LinkGeneric 02/2024 - 01/2015
3	venetoclaxIBA 01/2023 - 01/2016
3	Histone Deacetylases (Histone Deacetylase)IBA 01/2022 - 10/2010
3	Drug CombinationsIBA 01/2022 - 09/2009
3	ProdrugsIBA 01/2019 - 06/2015
3	LigandsIBA 07/2016 - 03/2005
3	navitoclaxIBA 01/2016 - 03/2010
3	Asparaginase (Elspar)FDA Link 09/2015 - 09/2007
3	Vorinostat FDA Link 01/2015 - 09/2009
3	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2014 - 10/2010
3	ABT-737IBA 11/2013 - 09/2007
3	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 10/2010 - 03/2005
2	Topotecan (Hycamtin)FDA LinkGeneric 02/2024 - 05/2010
2	Etoposide (VP 16)FDA LinkGeneric 02/2024 - 10/2011
2	Auranofin (Ridaura)FDA Link 02/2024 - 01/2021
2	Long Noncoding RNAIBA 11/2023 - 10/2021
2	Cytokine Receptors (Cytokine Receptor)IBA 10/2023 - 11/2021
2	Immunoglobulin FragmentsIBA 10/2023 - 11/2021
2	Liposomes (Liposome)IBA 01/2023 - 01/2015
2	PanobinostatIBA 01/2022 - 01/2016
2	CBLC137IBA 01/2022 - 01/2020
2	Small Interfering RNA (siRNA)IBA 10/2021 - 11/2007
2	Dynamins (Dynamin)IBA 02/2021 - 12/2020
2	OT-82IBA 01/2020 - 01/2020
2	MLN 8237IBA 01/2019 - 11/2011
2	Immunoconjugates (Immunoconjugate)IBA 01/2019 - 04/2013
2	Messenger RNA (mRNA)IBA 01/2019 - 03/2014
2	PolymersIBA 01/2019 - 02/2008
2	birinapantIBA 02/2016 - 01/2016
2	Tyrosine (L-Tyrosine)FDA Link 01/2016 - 06/2008
2	PR-104AIBA 09/2015 - 03/2014
2	Cyclin-Dependent Kinase Inhibitor p16IBA 04/2013 - 11/2006
1	Interleukin-3 (Interleukin 3)IBA 02/2024
1	Disulfiram (Antabuse)FDA Link 02/2024
1	Mitoxantrone (Novantrone)FDA LinkGeneric 02/2024
1	ixazomibIBA 02/2024
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2024
1	UbiquitinIBA 02/2024
1	Proteasome InhibitorsIBA 02/2024
1	LipidsIBA 08/2023
1	Phosphatidylinositols (Phosphatidylinositol)IBA 08/2023
1	duvelisibIBA 08/2023
1	TAK-659IBA 06/2023
1	Proto-Oncogene Proteins c-bcl-2 (Proto Oncogene Proteins c bcl 2)IBA 01/2023
1	Interleukin-7 (Interleukin 7)IBA 01/2023
1	Bispecific AntibodiesIBA 01/2023
1	Therapeutic UsesIBA 01/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023
1	liposomal doxorubicin (Doxil)FDA Link 01/2023
1	Pimozide (Orap)FDA Link 01/2023
1	Azacitidine (5 Azacytidine)FDA Link 01/2023
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2023
1	Histone MethyltransferasesIBA 01/2022
1	Circulating Tumor DNAIBA 01/2022
1	Thymic Stromal LymphopoietinIBA 11/2021
1	ruxolitinibIBA 11/2021
1	Lipid NanoparticlesIBA 10/2021
1	lambda Spi-1IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	CateninsIBA 01/2021
1	GTP Phosphohydrolases (GTPases)IBA 12/2020
1	dynole 34-2IBA 12/2020
1	Clofarabine (Clolar)FDA Link 01/2020
1	Protein Kinases (Protein Kinase)IBA 01/2020

Therapy/Procedure

24	Therapeutics 11/2023 - 05/2004
13	Drug Therapy (Chemotherapy) 02/2024 - 11/2007
3	Precision Medicine 01/2023 - 11/2020
1	Heterologous Transplantation (Xenotransplantation) 01/2022